Gene therapy research targets osteoarthritis

first_img Previous Article Next Article Related posts:No related photos. Comments are closed. Gene therapy research targets osteoarthritisOn 1 Nov 2002 in Personnel Today A team of scientists at the University of Manchester is hopeful that aresearch project could lead to an effective new treatment for the millions ofpeople in the UK who suffer from osteoarthritis. The team at the School of Biological Science believe they can slow down orpossibly even prevent the development of osteoarthritis by developing atargeted gene therapy over the next five years. If their approach is successful, it could lead to clinical trials onpatients within the next decade. The team’s work is being funded by a five-yeargrant of almost £685,000 from medical research charity the Arthritis ResearchCampaign. Around two million people in the UK have osteoarthritis, the most commonform of arthritis. The number of people with the condition is rising as thepopulation’s age and weight increase. “We’re very optimistic. We’ve been working towards this for about 10years now, and we’re at the point where we can talk about developing a treatment,”said Gillian Wallis, a senior lecturer in medicine, who, together with RayBoot-Hanford, a reader in molecular biology, is leading the research programme “We are still very much at the research stage, but if all ourlaboratory experiments work out then we hope to translate the results directlyinto clinical practice. We would hope to be looking at clinical trials onpatients within 10 years,” she added. The only currently available treatments for osteoarthritis are non-steroidalanti-inflammatory drugs (NSAIDs) that alleviate symptoms but do not stop theprogress of the disease. But many patients cannot tolerate these drugs because of side effects. read more

Equinor completes drilling at wildcat well 31/5-7 in North Sea

first_img The Northern Lights template prior to installation on the seabed. (Credit: Equinor ASA) Equinor and its partners Shell and Total have completed drilling of wildcat well 31/5-7 Eos located about 2500m subsea in exploitation licence 001in the North Sea.The well has been drilled 17.5km southwest of Troll A in the northern part of the North Sea to assess the suitability of the reservoir rocks in the Johansen formation for storage of carbon dioxide (CO2).Equinor project development senior vice-president Geir Tungesvik said: “This is an important milestone in realising the possibility of a CO₂ storage on the Norwegian continental shelf.“The preliminary results from the well so far have been positive. The drilling results will now be further analysed before concluding.”Equinor said that the firms have proved a sealing shale layer and the presence of good quality sandstone in the reservoir.In the Cook and Johansen Formations, where plans are underway for CO2 store project, Equinor has encountered a total of 173m of sandstone, with good to very good reservoir quality.Additionally, the well had encountered 75m of sealing homogeneous shale in the Lower Drake Formation, above the sandstone reservoir.Norwegian Petroleum Directorate CO2 storage project coordinator Eva Halland said: “That was also the case here, where we not only hoped to prove a water-filled reservoir, but a reservoir that would be well suited for injection and storage of CO2.”Equinor acquires extensive amounts of data following drilling programmeEquinor and its partners have acquired extensive amounts of data have through coring, logging, sampling and a production test.The data will now be assessed for making an investment decision for the Norwegian full-scale project, Northern Lights, for capture, transport and storage of CO2.The well 31/5-7 is planned to be used for injection and storage of CO₂ as part of Northern Lights project.The well was drilled to a vertical depth of 2884m using West Hercules drilling facility and was terminated in the Statfjord Group in the Lower Jurassic. Its is planned to be temporarily plugged and abandoned. The wildcat well 31/5-7 drilling was aimed to assess the suitability of the reservoir rocks in the Johansen formation for storage of CO2last_img read more


first_img(C) RIVERBOAT – COMMISSIONERS Red denotes Personnel and Finance meetingBlue denotes County Council meeting APPROPRIATION ORDINANCE:(A) LOIT SPECIAL DISTRIBUTION(B) CONVENTION CENTER OPERATINGREPEAL: (A)TRANSFERS: (A) SHERIFF(B) JAILOLD BUSINESS: (A)NEW BUSINESS: (E)  HIGHWAY1. Request to fill the vacancy for Secretary(F) PROSECUTOR – VICTIM-WITNESS ASSISTANCE 1. Request to fill a vacancy for Victim Advocate (A) PERSONNEL ADMINISTRATION COMMITTEE: 1. REQUEST REFERRAL TO BKDa. SUPERIOR COURT – IDOC/BUSINESS DIRECTOR(B)  CLERK/Request to increase Early Voting & Election Day poll worker pay(C)  RESOLUTION/Amending Resolution related to certain Redevelopment District Tax Increment Revenue Bonds & Related Matters12. AMENDMENTS TO SALARY ORDINANCE: AGENDA Of The VANDERBURGH COUNTY COUNCILon April 3, 2019, 3:30 P.M. in ROOM 301OPENING OF MEETINGATTENDANCE ROLL CALLPLEDGE OF ALLEGIANCEINVOCATIONAPPROVAL OF MINUTES:(A) Personnel & Finance February 27, 2019 (B) County Council March 6, 2019PERSONNEL REQUESTS:(A) SUPERIOR COURT / DADS1. Request to fill the vacancy for Administrative Assistant/Office Manager(B) SHERIFF1. Request to change Court Screener to Deputy Sheriff and fill vacancy 2. Request to fill the vacancy for Deputy Sheriff(C) HEALTH DEPARTMENTRequest to fill the vacancy for Administrative AideRequest to fill the vacancy for Part-time Administrative Aide (A) SHERIFF (2)(B) JAIL(C) DADS(D) HEALTH DEPARTMENT (2) center_img (D)  HEALTH DEPARTMENT – WICRequest to fill the vacancy for Health Educator/WICRequest to fill the vacancy for Registered Dietician/Registered Nurse (E) HIGHWAY(F) HEALTH DEPARTMENT – WIC (2)(G) PROSECUTOR – VICTIM-WITNESS ASSISTANCE (C) AUDITOR/COIT(D) COMMISSIONERS/COIT PERSONNEL AND FINANCE MEETING MARCH 27, 20193:30 P.M.ROOM 301 FacebookTwitterCopy LinkEmailShare PUBLIC COMMENTREMINDER NEXT MEETING DATE/TIME: April 24, 2019 @ 3:30 p.m.ADJOURNMENTlast_img read more

New program aims to keep remote workers engaged in their jobs

first_img Google+ (Photo supplied/Indiana Department of Workforce Development) The Indiana Chamber of Commerce has a new program that will help Hoosier employers develop their workforce and keep employees engaged as more businesses turn to remote work.Inside Indiana Business says the program is a partnership with Engage Mentoring and will be through the chamber’s Institute for Workforce Excellence.Jason Bearce, Vice President of Education and Workforce Development for the chamber, said the program will help employees with career development and connect them with mentors who can help them grow their skills.Click HERE for more information. By Network Indiana – July 17, 2020 1 223 Twitter Facebook Google+ WhatsApp Facebook CoronavirusIndianaLocalNews Previous articleCharges filed in 4th of July vehicle incident involving protestersNext articleLaPorte County Commissioners mandate face masks in public Network Indiana Pinterest Twitter Pinterest WhatsApp New program aims to keep remote workers engaged in their jobslast_img read more

Bob Seger Reschedules Canceled Tour After Recovering From Spinal Surgery

first_imgLast year, Detroit-native rocker and Rock and Roll Hall of Famer Bob Seger was forced to suddenly cancel the remainder of his tour after undergoing emergency spinal surgery to repair a ruptured disc in his neck three weeks into the trek. Today, after some speculation that the surgery may have sidelined him for good, Seger and the Silver Bullet Band have officially announced several rescheduled dates for later this year and into early 2019. The rescheduled run is set to begin on November 24th, 2018 at the Sprint Center in Kansas City, MO.As USA Today notes, “Rescheduled dates are being rolled out this morning for 13 of the 19 markets affected by the postponement. The remaining six makeup shows will be disclosed in coming weeks. … Shows are being announced at 7 a.m. locally in respective U.S. time zones. The first batch includes Greenville, S.C. (Dec. 20), Atlanta (Dec. 22) and Columbus (Jan. 19).”Bob Seger’s team also worked to try to match the rescheduled shows with the days of the week on which the original performances were booked (i.e., the rescheduled show for a postponed date slated for a Saturday night will take place on the weekend.) See below for the full list of rescheduled Bob Seger & the Silver Bullet Band tour dates which have been announced. For more information, or to purchase tickets, head to Seger’s website.Bob Seger Upcoming Rescheduled Tour DatesNov 24, 2018- Sprint Center – Kansas City, MONov 27, 2018 – Wells Fargo Arena – Des Moines, IANov 30, 2018 – Scottrade Center – St. Louis, MODec 12, 2018 – XCEL Energy Center – St. Paul, MNDec 14, 2018 – Allstate Arena – Chicago, ILDec 20, 2018 – Bon Secours Wellness Arena – Greenville, SCDec 22, 2018 – Infinite Energy Arena – Atlanta GAJan 19, 2019 – Nationwide Arena – Columbus, OHJan 29, 2019 – Rimrock Auto Arena – Billings, MTJan 31, 2019 – Ford Center – Boise, IDFeb 15, 2019 – Talking Stick Resort Arena – Phoenix, AZFeb 17, 2019 – Pepsi Center – Denver, COFeb 23, 2019 – The Forum – Inglewood, CAView All Tour Dates[H/T USA Today]last_img read more

Pollinator Plants

first_imgAs part of an ongoing effort to help support Georgians use more native plants in their landscapes, University of Georgia Cooperative Extension has partnered with the State Botanical Garden at the University of Georgia, the Georgia Green Industry Association and the Georgia Department of Agriculture to launch the state’s first Pollinator Plants of the Year Program. “We are excited to be part of the effort to get this amazing program in place for Georgia gardeners,” said Becky Griffin, UGA Extension school and community garden coordinator and pollinator protection expert. “Extension has strengths. The State Botanical Garden of Georgia has strengths; the Department of Agriculture has strengths and the private sector has its strengths. We have a better chance of meeting our goal of providing more pollinator habitat if we work together.”The collaboration will connect Georgia’s robust greenhouse industry with experts in native plant cultivation and pollinator health to produce more ready-to-plant natives and to encourage Georgians to turn part of their home landscape into pollinator habitat. This year the groups will be reaching out to greenhouse growers to encourage them to produce specially selected landscape plants. Next year the focus will be on teaching gardeners how to incorporate and maintain the pollinator-friendly plants. The State Botanical Garden at the University of Georgia announced its first Georgia Pollinator Plants of the Year at the Georgia Green Industry Association Wintergreen conference to encourage green industry professionals to suggest that businesses, parks, schools, city and county governments, and home gardeners add pollinator-friendly native plants to their landscapes.The plants were selected by a committee made up of horticulturists, ecologists, entomologists and industry professionals. Each plant had to be aesthetically pleasing, marketable and, most importantly, provide shelter and food for a number of native Georgia pollinators. “This program brings together conservation and horticulture, which don’t function independently—one supports the other,” said Lauren Muller, conservation outreach coordinator at the State Botanical Garden and coordinator of the Georgia Pollinator Plants of the Year program. “It is important for people in the green industry to think about conservation, the work we are doing and how we can tie it back into the larger ecological system.”The 2021 Pollinator Plants of the Year are:Spring bloomer — Conradina (Conradina canescens), also known as wild rosemary, is a fine-textured, evergreen, woody shrub in the mint family with aromatic, needle-like leaves. In spring, the plant is covered in small lavender flowers with purple-spotted throats. It supports many native bees and other pollinators and is ideal for container gardening or garden walls.Summer bloomer — Sweet Pepperbush (Clethra alnifolia) is a small, deciduous, densely branched shrub ideal for rain gardens. Panicles of white flowers give off an intoxicating fragrance in the heat of summer and support many native bees.Fall bloomer — Downy Goldenrod (Solidago petiolaris) — not to be confused with ragweed, the true culprit in many allergies — is one of the shorter goldenrods, standing between one and three feet tall. From August to October, the flowers bloom in dense, spiky clusters, creating a gorgeous yellow plume. This is an excellent plant for bees, wasps and at least 112 species of butterflies and moths.Georgia native — Butterfly Weed (Asclepias tuberosa) is a drought-tolerant, herbaceous perennial wildflower that reaches one to two feet tall and is excellent for sunny borders, meadows and containers. This plant serves as the larval host for the Monarch Butterfly, Grey Hairstreak, Queen Butterfly and Milkweed Tussock Moth and provides abundant nectar for many insects and hummingbirds.These plants should be available in Georgia garden centers in late 2020 and early 2021. “This is great because, as an agent, it’s discouraging when you get a call from someone asking where they can find these (native) plants and we have to say, ‘Good luck! You can start them from seed if you want,” said Ashley Hoppers, UGA Cooperative Extension agricultural and natural resources agent for Fannin County. “It really stifles their desire to plant natives because it’s hard. If (home gardeners) can’t go to a local outlet and find that (plant) they’re looking for, it creates a negative feedback loop.”The partnership behind the Pollinator Plants for the Year is part of a large scale partnership between State Botanical Garden and UGA Extension. Pollinator protection experts with Extension have merged their Pollinator Spaces project with the garden’s Connect to Protect pollinator protection efforts. The program will continue under Connect to Protect and help build a stronger pollinator protection movement across the state, Griffin said.The Georgia Department of Agriculture Georgia Grown’s Pollen Nation program will also join that effort. The program’s goal is to encourage the creation of pollinator gardens and the propagation of native plants, and to help support the green industry through increased plant sales of pollinator-friendly species, said Matthew Kulinski, deputy director of marketing at the Georgia Department of Agriculture.Pollen Nation will provide green industry professionals with marketing and educational materials and consumers a website with tips on the best pollinators for their landscapes, including the Georgia Pollinator Plants of the Year. That program will launch in March. Programs and partnerships like the Georgia Pollinator Plants of the Year program and Pollen Nation not only benefit members of the green industry, but also consumers and the environment, according to Jeremy Oxford, chairman of the Georgia Green Industry Association, which hosts the Wintergreen conference.“Connecting the dots between the environmental benefits of pollinator plants and Georgia’s nursery industry creates a win-win relationship,” Oxford said. “The Georgia Grown program and pollinator awards highlight the best of these plants so that growers can make them easily available to the consumer. “For information on acquiring Georgia Pollinator Plants of the Year or Connect to Protect visit information on how UGA Extension can help families, businesses and schools create more pollinator-friend landscapes visit read more

Leveraging technology to enhance branch health and safety

first_img 5SHARESShareShareSharePrintMailGooglePinterestDiggRedditStumbleuponDeliciousBufferTumblr,Tim Klatt As the Director of Retail Strategies for La Macchia Group, Tim Klatt brings over 15 years of experience in geographical market analysis, strategy development and large scale retail deployments for … Web: Details When it comes to the consumer journey, the branch banking experience has looked and felt the same for decades, and consumers were accepting of that. But, even before COVID-19, things were starting to change. In recent years, consumers have come to expect the same high-tech amenities at their banks and credit unions as they experience in other retail environments, balanced with the in-person, community-based financial expertise that occurs face-to-face in the physical branch. As “shelter at home” orders expire and branches across the nation reopen, not only will there be a continued need to balance the high-tech with the individualized, personal-relationship, but there will be a need to adapt in direct response to the wants and needs of the post-pandemic consumer.As a result, financial institutions must consider modifications that prioritize public health and safety – in a way that eases any fears, and projects a sense of security, safety and well-being for consumers and employees alike. There are multiple, baseline modifications branches can and should consider before reopening. Which solutions are right for each branch will be dependent on multiple factors, including the local impact of the pandemic and consumer sentiment. Simple modifications, like floor markers, acrylic partitions and sanitization stations, meet the immediate need and are critical to a reopening strategy; however, as we look to the branch of the future, we have an opportunity to seamlessly integrate these and more advanced safety elements to ensure a comfortable experience for the consumer. Through creative, adaptable design, a relationship-based, high-tech, AND high-safety branch can and should feel natural.Institutions will need to communicate digitally that they are ready for employees and patrons to return and will need to quickly demonstrate that they have created spaces and environments that prioritize public health and safety. Imagine a branch designed for social distancing, with the consumer journey mapped and managed to seamlessly control spacing and interaction.  Members and employees enter through automatic doors, never having to touch a handle.  Copper alloy surfaces that are anti-microbial as well as functional and aesthetically pleasing adorn properly spaced consultation stations.  In a space drenched in natural sunlight, UV-based disinfecting systems target high-touch, high-traffic areas.  Enhanced HVAC filtration systems continuously maintain the air quality of the physical space behind-the-scenes. These types of changes are key to the branch of the future, but there are even more things financial leaders can do.Understandably, much attention is being paid to the safety of the physical branch and the changes that will come. However, it’s important to consider how all your banking channels work together to promote and protect safety. Now may be the time for a paradigm shift.  Rather than physical vs digital channels, what if we looked at technology, including digital, as a foundational strategy to support and connect in-person service, remote service and self-service?  Would that enable financial leaders to more readily adapt to whatever challenges come their way?Looking ahead, technology will enable a better, safer branch experience and is key to integrating self-service and in-person service specifically.  With a fully tech-enabled journey, should a member want or need to visit a branch for something like opening an account or refinancing a loan, being able to schedule an appointment online will help to manage their time and expectations, and control branch traffic.  Enhancing that experience one step further, digital queuing enables staff to alert members waiting in the parking lot when it is safe to enter the lobby.In the not-so-distant future, once a member enters the branch, digital signage populated by a content management program can highlight the various ways the branch has been modified for their safety and include messaging on best-practices for in-branch interaction.  That content can easily be changed to feature promotions, new perks and even local community events.  During scheduled meetings, there will likely be an even greater desire to minimize the time physically spent in the branch, and a digital strategy that enables members to start something online (new account activation, a loan, etc.) and seamlessly continue the conversation in-branch will be highly valued.  For simple transactions, many ATMs can handle withdrawals and deposits, while an upgrade to or the addition of ITMs connected to core systems can help maintain physical distancing while providing personalized support via a remote video operator.  These are just a few of the many changes credit unions can make to create a better, safer experience by positioning digital or technology strategies at the center of their universe.There is no crystal ball showing us what the future holds. An investment in your future involves both quickly and effectively modifying your space to meet the immediate needs of today’s post-pandemic consumer, while keeping an eye toward investments that allow you to easily adapt to what the future might bring. The institutions that adapt will be the ones that thrive.last_img read more

Owners of this 1970s beach house are hoping to get lucky off their prime position

first_img8 Darwalla Ave, Currumbin.ALL three owners of this beachfront property could become be paper millionaires over night with help from their Currumbin unit block.Located at 8 Darwalla Ave, the beachfront property is on the market for $3.15 million. The home stretches out on 653sq m and comes with comes with 18m worth of golden beach frontage. One of the owners is soil scientist Dennis Baker who bought unit one of the three for $77,000 in 1983. “I couldn’t even afford it at the time but my wife and I agreed we would just get a loan and pay it off,” Mr Baker said.The father-of-three said he and his wife had been using it as a holiday-home for the past 15 years. “When we first inspected it we stepped off the street, through the front door and the right through the house to the sandy beach,” he said.“The kids bolted towards the sand.” 8 Darwalla Ave, Currumbin.Sophie Carter from Sophie Carter Exclusive Properties is marketing the property, Sandy Cove, and said the three-unit block is one of six left. “The whole property is on the market for the first time since it was built,” Ms Carter said. “Sandy Cove has never been inundated during cyclonic conditions and it sits in a natural cove that protects it from even the biggest tides or high seas,” she said. The property has a medium density residential and a three-storey height limit. 8 Darwalla Ave, Currumbin.Mr Baker said it has been his paradise ever since.More from news02:37Purchasers snap up every residence in the $40 million Siarn Palm Beach North6 hours ago02:37International architect Desmond Brooks selling luxury beach villa1 day ago“We love the Gold Coast, we decided to officially move from Brisbane and officially set up here.”While Mr Baker lives in Surfers Paradise he swears by taking a holiday on the southern end of the Gold Coast.“When the kids we’re young we spent six long weeks at that Currumbin unit,” he said. Mr Baker said he and the other two owners have agreed to sell the block after holding onto it tightly. “The unit block was originally built by the family in unit two, its been in their family for years,” he said.Mr Baker said the home reminded him of the 70s every time he stepped through the door. “It’s a bit of a flashback, with all the developments on the coast this place is a nice reminder of what life was once like.” last_img read more

Rural oasis for sale

first_img 523 Gieseman Rd will be open for inspection on Sunday from 3pm-3.45pm before the auction on-site on October 6 at 1pm. 523 Gieseman Rd, Black River 523 Gieseman Rd, Black RiverThe property has been broken up into 13 paddocks and if fully fenced while the modern house is made from timber and steel and has been designed for indoor and outdoor living.Ray White Kirwan agent Craig Currie said the home offered an ideal semirural lifestyle as it was still close to schools, shopping centres and infrastructure.“It has all the modern conveniences of a normal house in town but you’ve got 75 acres of land,” he said.“The way it’s been broken up into small paddocks works really well with grazing in the dry.“it would be perfect for horses and cattle.More from news01:21Buyer demand explodes in Townsville’s 2019 flood-affected suburbs12 Sep 202001:21‘Giant surge’ in new home sales lifts Townsville property market10 Sep 2020“It can also still be bought on a normal residential contract.” 523 Gieseman Rd, Black RiverAN EQUINE paradise with 75 acres of land and an immaculate homestead will be sold under the hammer on October 6.The four bedroom, two-bathroom, four car property complete with a swimming pool is located at 523 Giesman Rd, Black River.center_img 523 Giesman Rd, Black RiverThe property has a bore and two dams with water points in various locations.The homestead was built 12 years ago and has 325 sqm of under-roof space with rural views.Entry to the property is via a 600m long driveway lined with trees that has been raised to ensure the homestead is accessible in all weather conditions.A huge, 4m wide deck wraps around one side of the home and overlooks the in-ground swimming pool.Mr Currie said the owners are motivated to sells and would be considering offers before the auction.“The owners weren’t certain where it will sit in the current market and they wanted to get that feedback from the market which is why we’re going to auction,” he said.“The owners are very keen for this property to go.” For more information call Craig Currie on 0428 149 000.last_img read more

Lady Bulldogs Fall To Lady Knights In Softball

first_imgThe Batesville Lady Bulldogs lost to The SD Lady Knights 9-3 in Varsity Softball action.Batesville vs. SD Varsity Softball (4-10)The JV teams battle to  3-3 tie.Batesville vs. South Dearborn JV Softball (4-11)On Monday (4-13), The Lady Dogs will travel to EIAC rival East Central for a 5:30 varsity start time. JV to follow.Courtesy of Bulldogs Coach Jody Thomas.last_img